Although it was initially designed for office and IT environments, USB was quickly adopted by industry as well. Its simplicity and interoperability made it too useful to ignore. But USB has built-in vulnerabilities that can cause trouble when it is used in real-world applications. For example, its ability to carry 5 VDC power to peripherals means that USB devices are very susceptible to ground loops, electromagnetic interference (EMI), and electrostatic discharges (ESD).
B&B Electronics, USB, Harsh Environments